65974-52-9
65974-52-9
Chemical Structure
NCI126224
- CAS No.: 65974-52-9
- Formula:C12H11NO6
- Molecular Weight:265.22
InChIKey: LKLMASCOTOBEMT-UHFFFAOYSA-N
SMILES: O=C(/C(C(OC)=O)=C\C1=C([N+]([O-])=O)C=CC=C1)OC
Biological Activity: NCI126224 is a TLR4 signaling inhibitor. NCI126224 suppress LPS (HY-D1056)-induced production of NF-κB, TNF-α, IL-1β, and NO in the nanomolar-low micromolar range. NCI126224 can be used for the research of inflammatory diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NCI126224 | 99.77% | NCI126224 is a TLR4 signaling inhibitor. NCI126224 suppress LPS (HY-D1056)-induced production of NF-κB, TNF-α, IL-1β, and NO in the nanomolar-low micromolar range. NCI126224 can be used for the research of inflammatory diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.63
HY-400142(E)-4-(2-Nitrophenyl)-4-oxobut-2-enoic acid -
Similarity Score 0.59
HY-W101891Boc-2-nitro-L-phenylalanine -
Similarity Score 0.59
HY-W715444Mucidin -
Similarity Score 0.59
HY-106842Nitecapone -
Similarity Score 0.58
HY-W0024164-Nitro-L-phenylalanine methyl ester hydrochloride -
Similarity Score 0.58
HY-155784SPC-180002 -
Similarity Score 0.57
HY-W028991N-(4-Nitrobenzoyl)glycine -
Similarity Score 0.56
HY-753793-(4-Nitro-phenyl)-L-alanine ethyl ester hydrochloride -
Similarity Score 0.56
HY-105671Balazipone -
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