6631-94-3
Chemical Structure
ML171
Synonym(s): 2-Acetylphenothiazine; 2-APT
- CAS No.: 6631-94-3
- Formula:C14H11NOS
- Molecular Weight:241.31
IUPAC Name: 1-(10H-phenothiazin-2-yl)ethan-1-one
InChIKey: JWGBOHJGWOPYCL-UHFFFAOYSA-N
SMILES: CC(C1=CC=C2SC3=CC=CC=C3NC2=C1)=O
Biological Activity: ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay.
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ML171 | 99.53% | ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay. | ||||||||||||||||||||
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ML171 (Standard) | 98.62% | ML171 (Standard) is the analytical standard of ML171. This product is intended for research and analytical applications. ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay. | ||||||||||||||||||||
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Similarity Score 0.80
HY-W0119962-Methylthiophenothiazine -
Similarity Score 0.80
HY-I01782-Cyanophenothiazine -
Similarity Score 0.79
HY-W0122582-Methoxyphenothiazine -
Similarity Score 0.73
HY-W7196812-(Methoxy-d3)-10H-phenothiazine -
Similarity Score 0.70
HY-B1506Acepromazine -
Similarity Score 0.69
HY-A0243Aceprometazine -
Similarity Score 0.68
HY-120714Metiazinic acid -
Similarity Score 0.68
HY-128004ML171 analog 1 -
Similarity Score 0.67
HY-I0212RDibenzo[b,f][1,4]thiazepin-11(10H)-one (Standard) -
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