67346-48-9
Chemical Structure
(S,S)-Formoterol
Synonym(s): (+)-Formoterol
- CAS No.: 67346-48-9
- Formula:C19H24N2O4
- Molecular Weight:344.40
IUPAC Name: N-(2-hydroxy-5-((S)-1-hydroxy-2-(((S)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide
InChIKey: BPZSYCZIITTYBL-ORAYPTAESA-N
SMILES: O=CNC1=CC([C@H](O)CN[C@@H](C)CC2=CC=C(OC)C=C2)=CC=C1O
Biological Activity: (S,S)-Formoterol ((+)-Formoterol) is the (S,S)-enantiomer of Formoterol (HY-B0010B). (S,S)-Formoterol is a β2-adrenergic receptor (β2-adrenergic receptor) ligand. (S,S)-Formoterol can induce mast cell mediator release, peribronchial and perivascular inflammatory cell infiltration, basal airway tone, IFN-γ production, and IL-4 production. (S,S)-Formoterol acts through the β2-adrenergic receptor, altering its transduction pathways and modulating receptor structure and function. (S,S)-Formoterol can be used in the study of asthma[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S,S)-Formoterol | 95.83% | (S,S)-Formoterol ((+)-Formoterol) is the (S,S)-enantiomer of Formoterol (HY-B0010B). (S,S)-Formoterol is a β2-adrenergic receptor (β2-adrenergic receptor) ligand. (S,S)-Formoterol can induce mast cell mediator release, peribronchial and perivascular inflammatory cell infiltration, basal airway tone, IFN-γ production, and IL-4 production. (S,S)-Formoterol acts through the β2-adrenergic receptor, altering its transduction pathways and modulating receptor structure and function. (S,S)-Formoterol can be used in the study of asthma. | ||||||||||||||||||||
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References
- [1]. Abraha D, et al. (S,S)-formoterol increases the production of IL-4 in mast cells and the airways of a murine asthma model. Int Arch Allergy Immunol. 2004 Apr;133(4):380-8. [Content Brief]
- [2]. Steinke JW, et al. Opposing actions of (R,R)-isomers and (S,S)-isomers of formoterol on T-cell function. J Allergy Clin Immunol. 2006 Oct;118(4):963-5.
