67605-85-0
67605-85-0
Chemical Structure
N-Butanoyl-L-homoserine lactone
Synonym(s): C4-HSL; N-Butyryl-L-homoserine lactone
- CAS No.: 67605-85-0
- Formula:C8H13NO3
- Molecular Weight:171.20
IUPAC Name: (S)-N-(2-oxotetrahydrofuran-3-yl)butyramide
InChIKey: VFFNZZXXTGXBOG-LURJTMIESA-N
SMILES: CCCC(N[C@H]1CCOC1=O)=O
Biological Activity: N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Butanoyl-L-homoserine lactone | 98.77% | N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa. | ||||||||||||||||||||
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N-Butanoyl-L-homoserine lactone (Standard) | 99.83% | N-Butanoyl-L-homoserine lactone (Standard) (C4-HSL (Standard)) is the analytical standard of N-Butanoyl-L-homoserine lactone (HY-114816). This product is intended for research and analytical applications. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa. | ||||||||||||||||||||
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N-butyryl-L-Homoserine lactone-d5 | N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa. | |||||||||||||||||||||
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References
- [1]. Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1
- [2]. Zhao M, et al. C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis. PLoS One. 2019 Feb 19;14(2):e0212041. [Content Brief]
- [3]. Feng Sun, et al. Advance of the diversity of bacterial quorum sensing and quorum quenching. National Natural Science Foundation of China. Published online 9 October 2018.
