67953-08-6

GPNA hydrochloride Chemical Structure
67953-08-6

Chemical Structure

GPNA hydrochloride

  • CAS No.: 67953-08-6
  • Formula:C11H14ClN3O5
  • Molecular Weight:303.70

IUPAC Name: N5-(4-nitrophenyl)-L-glutamine hydrochloride

InChIKey: OJEVFSFTVARWQX-FVGYRXGTSA-N

SMILES: OC([C@@H](N)CCC(NC1=CC=C([N+]([O-])=O)C=C1)=O)=O.[H]Cl

Biological Activity: GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells[1].

Cat. No. Product Name Purity Description Pricing
HY-W011391
GPNA hydrochloride 99.72% GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells.
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