6830-03-1
6830-03-1
Chemical Structure
ω-Muricholic Acid
- CAS No.: 6830-03-1
- Formula:C24H40O5
- Molecular Weight:408.57
IUPAC Name: (R)-4-((3R,5R,6R,7R,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChIKey: DKPMWHFRUGMUKF-NTPBNISXSA-N
SMILES: C[C@@H]([C@]1(CC[C@]2([C@@]3([C@H]([C@@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)O)[H])O)O)[H])[H])[H])CCC(O)=O
Biological Activity: ω-Muricholic Acid is a bile acid. ω-Muricholic Acid is a metabolite of chenodeoxycholic acid in jaundiced mice. ω-Muricholic Acid can be used for the research of surgically jaundiced[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ω-Muricholic Acid | 99.2% | ω-Muricholic Acid is a bile acid. ω-Muricholic Acid is a metabolite of chenodeoxycholic acid in jaundiced mice. ω-Muricholic Acid can be used for the research of surgically jaundiced. | ||||||||||||||||||||
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ω-Muricholic Acid-d5 | ω-Muricholic Acid-d5 is the deuterium labeled ω-Muricholic Acid. | |||||||||||||||||||||
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ω-Muricholic acid-d4 | ω-Muricholic acid-d4 (ω-MCA-d4) is deuterium labeled ω-Muricholic Acid. ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid. | |||||||||||||||||||||
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Hyocholic Acid (Standard) | ≥98% | Hyocholic Acid (Standard) is the analytical standard of Hyocholic Acid. This product is intended for research and analytical applications. Hyocholic Acid is a bile acid found in pig. Hyocholic Acid can also be found in urine samples from patients with cholestasis. Hyocholic Acid promotes GLP-1 secretion via activating TGR5 and inhibiting FXR in enteroendocrine cells. Hyocholic Acid is known for its exceptional resistance to type 2 diabetes . | ||||||||||||||||||||
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Obeticholic acid | 99.94% | Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy. | ||||||||||||||||||||
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β-Muricholic acid | 99.92% | β-Muricholic acid is a potent and orally active biliary cholesterol-desaturating agent. β-Muricholic acid prevents cholesterol gallstones. β-Muricholic acid inhibits lipid accumulation. β-Muricholic acid has the potential for the research of nonalcoholic fatty liver disease (NAFLD). | ||||||||||||||||||||
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Ursodeoxycholic acid (Standard) | 99.83% | Ursodeoxycholic acid (Standard) is the analytical standard of Ursodeoxycholic acid. This product is intended for research and analytical applications. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active. | ||||||||||||||||||||
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Chenodeoxycholic acid-13C | 98.0% | Chenodeoxycholic acid-13C is the 13C-labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism. | ||||||||||||||||||||
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Murideoxycholic acid | 99.92% | Murideoxycholic acid is a 6 beta-hydroxylated bile acid. | ||||||||||||||||||||
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Hyodeoxycholic acid (Standard) | 99.61% | Hyodeoxycholic acid (Standard) is the analytical standard of Hyodeoxycholic acid. This product is intended for research and analytical applications. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells. | ||||||||||||||||||||
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3α,6α,7α,12α-Tetrahydroxy bile acid | 3α,6α,7α,12α-Tetrahydroxy bile acid is a hydrophilic tetrahydroxy derivative of bile acids. | |||||||||||||||||||||
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3α,6β,7α,12α-Tetrahydroxy bile acid | 3α,6β,7α,12α-Tetrahydroxy bile acid is a tetrahydroxy derivative of bile acids. | |||||||||||||||||||||
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