690206-97-4
Chemical Structure
ZM 306416
Synonym(s): CB 676475
- CAS No.: 690206-97-4
- Formula:C16H13ClFN3O2
- Molecular Weight:333.75
IUPAC Name: N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
InChIKey: YHUIUSRCUKUUQA-UHFFFAOYSA-N
SMILES: COC1=CC2=NC=NC(NC3=C(F)C=C(Cl)C=C3)=C2C=C1OC
Biological Activity: ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50s of 0.1 and 2 μM for KDR and Flt, respectively. ZM-306416 is also a EGFR inhibitor with an IC50 of <10 nM.
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ZM 306416 | 99.80% | ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50s of 0.1 and 2 μM for KDR and Flt, respectively. ZM-306416 is also a EGFR inhibitor with an IC50 of <10 nM. | ||||||||||||||||||||
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ZM 306416 (Standard) | ≥98% | ZM 306416 (Standard) is the analytical standard of ZM 306416. This product is intended for research and analytical applications. ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50s of 0.1 and 2 μM for KDR and Flt, respectively. ZM-306416 is also a EGFR inhibitor with an IC50 of <10 nM. | ||||||||||||||||||||
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Keywords