70677-47-3
Chemical Structure
Canniprene
- CAS No.: 70677-47-3
- Formula:C21H26O4
- Molecular Weight:342.43
IUPAC Name: 3-(3-hydroxy-5-methoxyphenethyl)-6-methoxy-2-(3-methylbut-2-en-1-yl)phenol
InChIKey: NGQFSSVGVDXEOE-UHFFFAOYSA-N
SMILES: OC1=C(OC)C=CC(CCC2=CC(OC)=CC(O)=C2)=C1C/C=C(C)\C
Biological Activity: Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa, is a potent inhibitor of 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; IC50=10 μM). Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins[1].
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Canniprene | 98.0% | Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa, is a potent inhibitor of 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; IC50=10 μM). Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins. | ||||||||||||||||||||
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Keywords
