70797-11-4
Chemical Structure
Cefpiramide
Synonym(s): SM-1652 free acid; Wy-44635 free acid
- CAS No.: 70797-11-4
- Formula:C25H24N8O7S2
- Molecular Weight:612.64
IUPAC Name: (6R,7R)-7-((R)-2-(4-hydroxy-6-methylnicotinamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: PWAUCHMQEXVFJR-PMAPCBKXSA-N
SMILES: O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@H](NC([C@H](NC(C4=C(O)C=C(C)N=C4)=O)C5=CC=C(O)C=C5)=O)C1=O)O
Biological Activity: Cefpiramide (SM-1652 free acid) is a cephalosporin antibiotic. Cefpiramide binds the MtrA DNA-binding domain and penicillin-binding proteins FtsI/PBP1A/B. Cefpiramide shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide is moderately susceptible to β-lactamase. Cefpiramide can be used for the research of tuberculosis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cefpiramide | 99.72% | Cefpiramide (SM-1652 free acid) is a cephalosporin antibiotic. Cefpiramide binds the MtrA DNA-binding domain and penicillin-binding proteins FtsI/PBP1A/B. Cefpiramide shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide is moderately susceptible to β-lactamase. Cefpiramide can be used for the research of tuberculosis. | ||||||||||||||||||||
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Similarity Score 0.93
HY-B0798Cefpiramide sodium -
Similarity Score 0.73
HY-B0210RCefoperazone (Standard) -
Similarity Score 0.72
HY-B0210CCefoperazone dihydrate -
Similarity Score 0.70
HY-B0210SCefoperazone-d5 -
Similarity Score 0.69
HY-B0210ARCefoperazone sodium salt (Standard) -
Similarity Score 0.65
HY-B1128Cefamandole -
Similarity Score 0.62
HY-123024Cefatrizine -
Similarity Score 0.61
HY-B1128BCefamandole lithium -
Similarity Score 0.61
HY-B1128ACefamandole sodium -
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References
- [1]. Barry AL, et al. Cefpiramide: comparative in-vitro activity and beta-lactamase stability. J Antimicrob Chemother. 1985 Sep;16(3):315-25. [Content Brief]
- [2]. Sato K, et al. Pharmacokinetics and bacteriological efficacies of apalcillin and cefpiramide in experimental pneumococcal meningitis. Antimicrob Agents Chemother. 1984 Oct;26(4):578-9. [Content Brief]
- [3]. Rangaraj S, et al. Cefpiramide Restricts Mycobacterium tuberculosis Growth by Binding to the DNA-Binding Domain of an Essential Response Regulator, MtrA. ACS Med Chem Lett. 2026 Jun 29;17(7):1563-1572.
