7239-48-7
Chemical Structure
Colistin B
Synonym(s): Polymyxin E2
- CAS No.: 7239-48-7
- Formula:C52H98N16O13
- Molecular Weight:1155.43
InChIKey: KNIWPHSUTGNZST-SSWRVQTPSA-N
SMILES: CC(C)CCCCC(N[C@@H](CCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCN)C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC1)=O)([H])[C@H](O)C)=O)CCN)=O)CCN)=O)CC(C)C)=O)CC(C)C)=O)CCN)=O)=O)=O)=O)=O
Biological Activity: Colistin B (Polymyxin E2) is a major component of Colistin (HY-113678) and also an antibacterial agent active against multidrug-resistant Gram-negative bacteria. Colistin B exerts apoptotic effects on human renal proximal tubular cells. Colistin B induces mild to moderate renal histological damage in mouse models. Colistin B can be used in the research of multidrug-resistant Gram-negative bacterial infections[1].
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Colistin B | Colistin B (Polymyxin E2) is a major component of Colistin (HY-113678) and also an antibacterial agent active against multidrug-resistant Gram-negative bacteria. Colistin B exerts apoptotic effects on human renal proximal tubular cells. Colistin B induces mild to moderate renal histological damage in mouse models. Colistin B can be used in the research of multidrug-resistant Gram-negative bacterial infections. | |||||||||||||||||||||
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