762242-59-1
762242-59-1
Chemical Structure
Clathrin-IN-4
- CAS No.: 762242-59-1
- Formula:C17H18Br2N2O
- Molecular Weight:426.15
IUPAC Name: (R)-1-(3,6-dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol
InChIKey: XUBJEDZHBUPBKL-CYBMUJFWSA-N
SMILES: CN(C[C@H](CN1C2=CC=C(C=C2C3=CC(Br)=CC=C31)Br)O)C
Biological Activity: Clathrin-IN-4 (compound 8b), a Wiskostatin?(HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM[1].
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Clathrin-IN-4 | 99.54% | Clathrin-IN-4 (compound 8b), a Wiskostatin?(HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM. | ||||||||||||||||||||
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References
Keywords
