7759-35-5
Chemical Structure
Nestoron
Synonym(s): ST-1435; Elcometrine
- No. CAS: 7759-35-5
- Formula:C23H30O4
- Molecular Weight:370.48
IUPAC Name: (8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylene-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
InChIKey: CKFBRGLGTWAVLG-GOMYTPFNSA-N
SMILES: CC([C@]1(OC(C)=O)[C@@]2([C@]([H])([C@@]3(CCC4=CC(CC[C@@]4([C@]3(CC2)[H])[H])=O)[H])CC1=C)C)=O
Biological Activity: Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive[1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Nestoron | 98.77% | Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive. | ||||||||||||||||||||
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Similarity Score 0.72
HY-121677Norgestomet -
Similarity Score 0.70
HY-U00091Gestonorone Capronate -
Similarity Score 0.70
HY-111614Melengestrol acetate -
Similarity Score 0.68
HY-B1710Norethindrone acetate -
Similarity Score 0.66
HY-105634ANomegestrol acetate -
Similarity Score 0.66
HY-N0347R17α-Hydroxyprogesterone acetate (Standard) -
Similarity Score 0.64
HY-Z9071Medroxyprogesterone acetate impurity 3 -
Similarity Score 0.64
HY-B0469RMedroxyprogesterone acetate (Standard) -
Similarity Score 0.62
HY-Z9070Medroxyprogesterone acetate impurity 1 -
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References
- [1]. Prasad PV, et al. Single-dose pharmacokinetics of Nestorone, a potential female-contraceptive.Steroids. 2010 Mar;75(3):252-64. Epub 2010 Jan 11. [Content Brief]
- [2]. Hussain R, et al. Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors. Endocrinology. 2011 Oct;152(10):3820-31. [Content Brief]
