78967-07-4
78967-07-4
Chemical Structure
Mofezolac
- CAS No.: 78967-07-4
- Formula:C19H17NO5
- Molecular Weight:339.34
IUPAC Name: 2-(3,4-bis(4-methoxyphenyl)isoxazol-5-yl)acetic acid
InChIKey: DJEIHHYCDCTAAH-UHFFFAOYSA-N
SMILES: O=C(O)CC1=C(C2=CC=C(OC)C=C2)C(C3=CC=C(OC)C=C3)=NO1
Biological Activity: Mofezolac, a non-steroidal anti-inflammatory drug (NSAID), is a selective, reversible and orally active COX-1 inhibitor with an IC50 of 1.44 nM. Mofezolac shows weak inhibitory activity on COX-2 (IC50 of 447 nM). Mofezolac can relieve pain and has anti-inflammatory activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mofezolac | 98.90% | Mofezolac, a non-steroidal anti-inflammatory drug (NSAID), is a selective, reversible and orally active COX-1 inhibitor with an IC50 of 1.44 nM. Mofezolac shows weak inhibitory activity on COX-2 (IC50 of 447 nM). Mofezolac can relieve pain and has anti-inflammatory activities. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.68
HY-162167COX-1-IN-1 -
Similarity Score 0.59
HY-121856Flumizole -
Similarity Score 0.59
HY-123535P18IN003 -
Similarity Score 0.58
HY-144441NSC81111 -
Similarity Score 0.57
HY-151620Antitumor agent-80 -
Similarity Score 0.56
HY-Z6409Palbociclib impurity 1 -
Similarity Score 0.56
HY-W0977654,4'-Dimethoxy-1,1'-biphenyl -
Similarity Score 0.56
HY-W1244004,4''-Dimethoxy-1,1':4',1''-terphenyl -
Similarity Score 0.55
HY-W038820RParecoxib sodium impurity 10 (Standard) -
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