80-59-1
80-59-1
Chemical Structure
Tiglic acid
- CAS No.: 80-59-1
- Formula:C5H8O2
- Molecular Weight:100.12
IUPAC Name: (E)-2-methylbut-2-enoic acid
InChIKey: UIERETOOQGIECD-ONEGZZNKSA-N
SMILES: C/C=C(C)/C(O)=O
Biological Activity: Tiglic acid is a monocarboxylic unsaturated organic acid. Tiglic acid can be isolated from croton oil. Tiglic acid agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity. Tiglic acid can be used in the research of obesity, diabetes, and inflammatory diseases[1][2][3].
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Tiglic acid | 99.74% | Tiglic acid is a monocarboxylic unsaturated organic acid. Tiglic acid can be isolated from croton oil. Tiglic acid agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity. Tiglic acid can be used in the research of obesity, diabetes, and inflammatory diseases. | ||||||||||||||||||||
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Tiglic acid (Standard) | ≥98% | Tiglic acid (Standard) is the analytical standard of Tiglic acid (HY-W012999). This product is intended for research and analytical applications. Tiglic acid is a monocarboxylic unsaturated organic acid. Tiglic acid can be isolated from croton oil. Tiglic acid agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity. Tiglic acid can be used in the research of obesity, diabetes, and inflammatory diseases. | ||||||||||||||||||||
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(E)-2-Methylbut-2-enoic-4,4,4-d3 acid | (E)-2-Methylbut-2-enoic-4,4,4-d3 acid is the deuterium labeled Tiglic acid (HY-W012999). Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite. | |||||||||||||||||||||
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References
- [1]. ROBERT E. BUCKLES, et al. THE PREPARATION OF TIGLIC AND ANGELIC ACIDS AND ESTERS. Cite This:J. Org. Chem.1950153680-684.
- [2]. Larraufie P, et al. SCFAs strongly stimulate PYY production in human enteroendocrine cells. Sci Rep. 2018 Jan 8;8(1):74. [Content Brief]
- [3]. Wang HQ, et al. Hydroxylated Ethacrylic and Tiglic Acid Derivatives from the Stems and Branches of Enkianthus chinensis and Their Potential Anti-inflammatory Activities. J Nat Prod. 2020 Oct 23;83(10):2867-2876. [Content Brief]
