82131-85-9
82131-85-9
Chemical Structure
SMARCA2-IN-10
- CAS No.: 82131-85-9
- Formula:C28H20N2O7
- Molecular Weight:496.47
IUPAC Name: 2-((2-(cyclohexylcarbamoyl)phenyl)carbamoyl)benzoic acid
InChIKey: DCXQKOZJGJDLKU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1C(O)=O)NC2=CC=C(OC3=CC=C(NC(C4=CC=CC=C4C(O)=O)=O)C=C3)C=C2
Biological Activity: SMARCA2-IN-10 (Compound 4) is a highly selective SMARCA2 ATPase domain inhibitor (IC50=17.676 μM). SMARCA2-IN-10 induces cell death in SMARCA4-deficient tumors. SMARCA2-IN-10 is promising for research of SMARCA4-mutant non-small cell lung cancer, small cell ovarian carcinoma, and melanoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SMARCA2-IN-10 | 96.05% | SMARCA2-IN-10 (Compound 4) is a highly selective SMARCA2 ATPase domain inhibitor (IC50=17.676 μM). SMARCA2-IN-10 induces cell death in SMARCA4-deficient tumors. SMARCA2-IN-10 is promising for research of SMARCA4-mutant non-small cell lung cancer, small cell ovarian carcinoma, and melanoma. | ||||||||||||||||||||
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References
Keywords
