SMARCA2-IN-10
Based on 1 Customer Validation
SMARCA2-IN-10 (Compound 4) is a highly selective SMARCA2 ATPase domain inhibitor (IC50=17.676 μM). SMARCA2-IN-10 induces cell death in SMARCA4-deficient tumors. SMARCA2-IN-10 is promising for research of SMARCA4-mutant non-small cell lung cancer, small cell ovarian carcinoma, and melanoma.
For research use only. We do not sell to patients.
- Purity: 96.05%
- CAS No.: 82131-85-9
- Formula: C28H20N2O7
- Molecular Weight:496.47
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All SWI/SNF Complex Isoforms
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Biological Activity
Chemical Information
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CAS No. 82131-85-9
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Appearance Solid
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Molecular Weight 496.47
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Formula C28H20N2O7
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Color White to off-white
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SMILES
O=C(C1=CC=CC=C1C(O)=O)NC2=CC=C(OC3=CC=C(NC(C4=CC=CC=C4C(O)=O)=O)C=C3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 62.5 mg/mL (125.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0142 mL | 10.0711 mL | 20.1422 mL | 50.3555 mL |
| 5 mM | 0.4028 mL | 2.0142 mL | 4.0284 mL | 10.0711 mL | |
| 10 mM | 0.2014 mL | 1.0071 mL | 2.0142 mL | 5.0356 mL | |
| 15 mM | 0.1343 mL | 0.6714 mL | 1.3428 mL | 3.3570 mL | |
| 20 mM | 0.1007 mL | 0.5036 mL | 1.0071 mL | 2.5178 mL | |
| 25 mM | 0.0806 mL | 0.4028 mL | 0.8057 mL | 2.0142 mL | |
| 30 mM | 0.0671 mL | 0.3357 mL | 0.6714 mL | 1.6785 mL | |
| 40 mM | 0.0504 mL | 0.2518 mL | 0.5036 mL | 1.2589 mL | |
| 50 mM | 0.0403 mL | 0.2014 mL | 0.4028 mL | 1.0071 mL | |
| 60 mM | 0.0336 mL | 0.1679 mL | 0.3357 mL | 0.8393 mL | |
| 80 mM | 0.0252 mL | 0.1259 mL | 0.2518 mL | 0.6294 mL | |
| 100 mM | 0.0201 mL | 0.1007 mL | 0.2014 mL | 0.5036 mL |
SMARCA2-IN-10 Related Classifications
HY-W494890 Related Classifications
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