822-17-3
822-17-3
Chemical Structure
Linoleate sodium
- CAS No.: 822-17-3
- Formula:C18H31NaO2
- Molecular Weight:302.43
IUPAC Name: sodium (9Z,12Z)-octadeca-9,12-dienoate
InChIKey: WYPBVHPKMJYUEO-NBTZWHCOSA-M
SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(O[Na])=O
Biological Activity: Linoleate sodium is an orally active IL8 regulator via the JNK and NF-κB pathway. Linoleate sodium can change the composition of fatty acids and the production of metabolites in cells. Linoleate sodium has anti-inflammatory, immune-regulating, and tumor cell growth-affecting activities[1][2][3][4][5][6][7][8][9].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Linoleate sodium | 99.88% | Linoleate sodium is an orally active IL8 regulator via the JNK and NF-κB pathway. Linoleate sodium can change the composition of fatty acids and the production of metabolites in cells. Linoleate sodium has anti-inflammatory, immune-regulating, and tumor cell growth-affecting activities. | ||||||||||||||||||||
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References
- [1]. Pan Z, et al. Effects of linoleate on cell viability and lipid metabolic homeostasis in goose primary hepatocytes. Comp Biochem Physiol A Mol Integr Physiol. 2011 Jun;159(2):113-8. [Content Brief]
- [2]. Maruyama H, et al. Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells. Lipids Health Dis. 2014 May 13;13:78. [Content Brief]
- [3]. Mulligan CM, et al. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. Cardiovasc Res. 2012 Jun 1;94(3):460-8. [Content Brief]
- [4]. Flick PK, et al. Effect of dietary linoleate on synthesis and degradation of fatty acid synthetase from rat liver. J Biol Chem. 1977 Jun 25;252(12):4242-9. [Content Brief]
- [5]. Oh-hashi K, et al. Reevaluation of the effect of a high alpha-linolenate and a high linoleate diet on antigen-induced antibody and anaphylactic responses in mice. Biol Pharm Bull. 1997 Mar;20(3):217-23. [Content Brief]
- [6]. Matsuba S, et al. Effect of dietary linoleate/alpha-linolenate balance on experimentally induced gastric injury in rats. Prostaglandins Leukot Essent Fatty Acids. 1998 Nov;59(5):317-23. [Content Brief]
- [7]. Norman A, et al. Antitumor activity of sodium linoleate. Nutr Cancer. 1988;11(2):107-15. [Content Brief]
- [8]. Nakashima Y, et al. Effect of a high linoleate and a high alpha-linolenate diet on general behavior and drug sensitivity in mice. J Lipid Res. 1993 Feb;34(2):239-47. [Content Brief]
- [9]. Watanabe S, et al. Effect of dietary alpha-linolenate/linoleate balance on crescent type-anti-glomerular basement membrane nephritis in rats. Lipids. 1990 May;25(5):267-72. [Content Brief]
Keywords
