835-31-4
835-31-4
Chemical Structure
Naphazoline
Synonym(s): Naphthazoline
- CAS No.: 835-31-4
- Formula:C14H14N2
- Molecular Weight:210.27
IUPAC Name: 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole
InChIKey: CNIIGCLFLJGOGP-UHFFFAOYSA-N
SMILES: C1(CC2=C3C=CC=CC3=CC=C2)=NCCN1
Biological Activity: Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research[1][2].
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Naphazoline | 99.74% | Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research. | ||||||||||||||||||||
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Naphazoline (Standard) | ≥98% | Naphazoline (Standard) is the analytical standard of Naphazoline (HY-111326). This product is intended for research and analytical applications. Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytoKines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research. | ||||||||||||||||||||
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Naphazoline-d4 hydrochloride | Naphazoline-d4 (hydrochloride) is the deuterium labeled Naphazoline hydrochloride. | |||||||||||||||||||||
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References
- [1]. Quan L, et, al. Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. Mol Med Rep. 2016 Apr;13(4):3319-25. [Content Brief]
- [2]. Yamaguchi I, et, al. Central and peripheral adrenergic mechanisms regulating gastric secretion in the rat. J Pharmacol Exp Ther. 1977 Oct;203(1):125-31. [Content Brief]
