84258-25-3
84258-25-3
Chemical Structure
Doxifluridine-d2
Synonym(s): Ro 21-9738-d2;5-Fluoro-5'-deoxyuridine-d2;5'-DFUR-d2
- CAS No.: 84258-25-3
- Formula:C9H9D2FN2O5
- Molecular Weight:248.20
IUPAC Name: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(methyl-d2)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
InChIKey: ZWAOHEXOSAUJHY-WSRWZZNSSA-N
SMILES: O[C@H]1[C@@](N2C(NC(C(F)=C2)=O)=O)([H])O[C@@H]([C@H]1O)C([2H])[2H]
Biological Activity: Doxifluridine-d2 is the deuterium labeled Doxifluridine[1]. Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.
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Doxifluridine-d2 | Doxifluridine-d2 is the deuterium labeled Doxifluridine. Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM. | |||||||||||||||||||||
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Doxifluridine (Standard) | ≥98% | Doxifluridine (Standard) is the analytical standard of Doxifluridine. This product is intended for research and analytical applications. Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs. | ||||||||||||||||||||
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Doxifluridine-d3 | Doxifluridine-d3 is deuterated labeled Doxifluridine (HY-B0021). Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs. | |||||||||||||||||||||
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Doxifluridine | 99.44% | Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs. | ||||||||||||||||||||
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References
