85541-78-2
85541-78-2
Chemical Structure
(Glu2)-TRH
- CAS No.: 85541-78-2
- Formula:C15H22N4O6
- Molecular Weight:354.36
InChIKey: HYZBGWLLSXSYLX-GUBZILKMSA-N
SMILES: O=C([C@@H]1CCC(N1)=O)N[C@@H](CCC(O)=O)C(N2[C@@H](CCC2)C(N)=O)=O
Biological Activity: (Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH; HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS[1].
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(Glu2)-TRH | 99.96% | (Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH; HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS. | ||||||||||||||||||||
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