856765-68-9
856765-68-9
Chemical Structure
Ethyl cinnamate-d5
- CAS No.: 856765-68-9
- Formula:C11H7D5O2
- Molecular Weight:181.24
IUPAC Name: ethyl-d5 methanesulfonate
InChIKey: KBEBGUQPQBELIU-VVBJMPBNSA-N
SMILES: CCOC(/C=C/C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
Biological Activity: Ethyl cinnamate-d5 is the deuterium labeled Ethyl cinnamate[1]. Ethyl cinnamate is a fragrance ingredient used in many fragrance compounds. Ethyl cinnamate is a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues[2][3].
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Ethyl cinnamate-d5 | 99.70% | Ethyl cinnamate-d5 is the deuterium labeled Ethyl cinnamate. Ethyl cinnamate is a fragrance ingredient used in many fragrance compounds. Ethyl cinnamate is a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. | ||||||||||||||||||||
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Ethyl cinnamate (Standard) | ≥98% | Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta. | ||||||||||||||||||||
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Ethyl cinnamate | 99.80% | Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. S P Bhatia, et al. Fragrance material review on ethyl cinnamate. Food Chem Toxicol. 2007;45 Suppl 1:S90-4. [Content Brief]
- [3]. Anika Klingberg, et al. Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy. J Am Soc Nephrol. 2017 Feb28(2):452-459. [Content Brief]
