868592-56-7
868592-56-7
Chemical Structure
NIAD-4
- CAS No.: 868592-56-7
- Formula:C18H10N2OS2
- Molecular Weight:334.43
IUPAC Name: 2-((5'-(4-hydroxyphenyl)-[2,2'-bithiophen]-5-yl)methylene)malononitrile
InChIKey: KLFRZDOQQDHVSS-UHFFFAOYSA-N
SMILES: N#C/C(C#N)=C/C1=CC=C(C2=CC=C(C3=CC=C(O)C=C3)S2)S1
Biological Activity: NIAD-4 is a blood-brain barrier permeable fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1].
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NIAD-4 | 98.52% | NIAD-4 is a blood-brain barrier permeable fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM. | ||||||||||||||||||||
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References
Keywords
