878739-06-1

AZ 628 Chemical Structure
878739-06-1

Chemical Structure

AZ 628

  • CAS No.: 878739-06-1
  • Formula:C27H25N5O2
  • Molecular Weight:451.52

IUPAC Name: 3-(2-cyanopropan-2-yl)-N-(4-methyl-3-((3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)phenyl)benzamide

InChIKey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N

SMILES: O=C1N(C)C=NC2=C1C=C(C=C2)NC3=C(C)C=CC(NC(C4=CC(C(C#N)(C)C)=CC=C4)=O)=C3

Biological Activity: AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively.

Cat. No. Product Name Purity Description Pricing
HY-11004
AZ 628 99.44% AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively.
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