878739-06-1
Chemical Structure
AZ 628
- CAS No.: 878739-06-1
- Formula:C27H25N5O2
- Molecular Weight:451.52
IUPAC Name: 3-(2-cyanopropan-2-yl)-N-(4-methyl-3-((3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)phenyl)benzamide
InChIKey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
SMILES: O=C1N(C)C=NC2=C1C=C(C=C2)NC3=C(C)C=CC(NC(C4=CC(C(C#N)(C)C)=CC=C4)=O)=C3
Biological Activity: AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZ 628 | 99.44% | AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively. | ||||||||||||||||||||
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AZ 628 (Standard) | ≥98% | AZ 628 (Standard) is the analytical standard of AZ 628 (HY-11004). This product is intended for research and analytical applications. AZ 628 is a pan-Raf Kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively. | ||||||||||||||||||||
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