885060-08-2
Chemical Structure
(R)-Filanesib
Synonym(s): (R)-ARRY-520
- CAS No.: 885060-08-2
- Formula:C20H22F2N4O2S
- Molecular Weight:420.48
IUPAC Name: (R)-2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide
InChIKey: LLXISKGBWFTGEI-HXUWFJFHSA-N
SMILES: O=C(N1[C@](C2=CC=CC=C2)(CCCN)SC(C3=CC(F)=CC=C3F)=N1)N(OC)C
Biological Activity: (R)-Filanesib ((R)-ARRY-520) is an isomer of Filanesib (HY-15187). Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-Filanesib | 98.53% | (R)-Filanesib ((R)-ARRY-520) is an isomer of Filanesib (HY-15187). Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity. | ||||||||||||||||||||
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-
Similarity Score 1.00
HY-15187Filanesib -
Similarity Score 0.99
HY-15187CFilanesib hydrochloride -
Similarity Score 0.90
HY-15187BFilanesib TFA -
Similarity Score 0.77
HY-177246AMitotic kinesin-IN-1 hydrochloride -
Similarity Score 0.54
HY-122130SCH 2047069 -
Similarity Score 0.47
HY-125969Rtt109 inhibitor 1 -
Similarity Score 0.43
HY-136861Antibacterial agent 192 -
Similarity Score 0.42
HY-135710ADAMTS-5-IN-2 -
Similarity Score 0.42
HY-119331CFM-5 -
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