89199-99-5
Chemical Structure
Mulberrofuran H
- CAS No.: 89199-99-5
- Formula:C27H22O6
- Molecular Weight:442.46
IUPAC Name: 2-((2S)-9-hydroxy-2-methyl-5,6-dihydro-2H-2,6-methanobenzo[b]oxocin-4-yl)-5-(6-hydroxybenzofuran-2-yl)benzene-1,3-diol
InChIKey: ZVTKGVROAGDVCH-GPZGZDFJSA-N
SMILES: C[C@@]12CC(CC(C3=C(C=C(C4=CC5=C(C=C(O)C=C5)O4)C=C3O)O)=C2)C6=CC=C(O)C=C6O1
Biological Activity: Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.). Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities[1][2][3].
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Mulberrofuran H | Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.). Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities. | |||||||||||||||||||||
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References
- [1]. Fukai T, et al. Structure of mulberrofuran H, a novel 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.)[J]. Chemical and pharmaceutical bulletin, 1984, 32(2): 808-811.
- [2]. Kang J, et al. Five new diels-alder type adducts from the stem and root bark of Morus mongolica. Planta Med. 2006 Jan;72(1):52-9. [Content Brief]
- [3]. Paudel P, et al. Antioxidant and anti-browning property of 2-arylbenzofuran derivatives from Morus alba Linn root bark. Food Chem. 2020 Mar 30;309:125739. [Content Brief]
