908115-27-5
908115-27-5
Chemical Structure
SNX-5422
Synonym(s): PF-04929113
- CAS No.: 908115-27-5
- Formula:C25H30F3N5O4
- Molecular Weight:521.53
IUPAC Name: (1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl glycinate
InChIKey: AVDSOVJPJZVBTC-CTYIDZIISA-N
SMILES: FC(F)(C1=NN(C2=CC(N[C@@H]3CC[C@H](CC3)OC(CN)=O)=C(C=C2)C(N)=O)C(CC(C)(C4)C)=C1C4=O)F
Biological Activity: SNX-5422 (PF-04929113), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SNX-5422 | 98.72% | SNX-5422 (PF-04929113), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37 nM. | ||||||||||||||||||||
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Keywords
