91095-48-6
Chemical Structure
8-Epidiosbulbin E acetate
- CAS No.: 91095-48-6
- Formula:C21H24O7
- Molecular Weight:388.41
IUPAC Name: (2S,4aR,6S,6aS,7R,10R,11aR,11bS)-2-(furan-3-yl)-11b-methyl-4,8-dioxododecahydro-2H-7,10-methanooxepino[4,5-f]isochromen-6-yl acetate
InChIKey: DYSOIAQEKRDXRB-LKMUTLMISA-N
SMILES: CC(O[C@@H]1[C@@]([C@@](C(O2)=O)([H])C[C@@]2([H])C3)([H])[C@]3([H])[C@](C)(C[C@@H](C4=COC=C4)O5)[C@@](C5=O)([H])C1)=O
Biological Activity: 8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
8-Epidiosbulbin E acetate | 98.42% | 8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Lin D, et al. Role of Metabolic Activation in 8-Epidiosbulbin E Acetate-Induced Liver Injury: Mechanism of Action of the Hepatotoxic Furanoid. Chem Res Toxicol. 2016 Mar 21;29(3):359-66. [Content Brief]
- [2]. Shi W, et al. Metabolomic-transcriptomic landscape of 8-epidiosbulbin E acetate -a major diterpenoid lactone from Dioscorea bulbifera tuber induces hepatotoxicity. Food Chem Toxicol. 2020 Jan;135:110887. [Content Brief]
Keywords
