925069-34-7
925069-34-7
Chemical Structure
PI-273
- CAS No.: 925069-34-7
- Formula:C16H16ClN3O2S2
- Molecular Weight:381.90
IUPAC Name: 2-(3-(4-chlorobenzoyl)thioureido)-4-ethyl-5-methylthiophene-3-carboxamide
InChIKey: MIERMBQDBLFAFW-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC(NC(C2=CC=C(Cl)C=C2)=O)=S)SC(C)=C1CC)N
Biological Activity: PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis[1].
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PI-273 | 98.47% | PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis. | ||||||||||||||||||||
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PI-273 (Standard) | ≥98% | PI-273 (Standard) is the analytical standard of PI-273 (HY-103489). This product is intended for research and analytical applications. PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis. | ||||||||||||||||||||
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References
Keywords
