93076-87-0
93076-87-0
Chemical Structure
JNJ-3790339
- CAS No.: 93076-87-0
- Formula:C30H33N3OS
- Molecular Weight:483.67
IUPAC Name: 6-(2-(4-(di-p-tolylmethylene)piperidin-1-yl)ethyl)-3,7-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one
InChIKey: MWZVZNTXVKGMFA-UHFFFAOYSA-N
SMILES: O=C1C(CCN2CC/C(CC2)=C(C3=CC=C(C)C=C3)\C4=CC=C(C)C=C4)=C(C)N=C5SC=C(C)N51
Biological Activity: JNJ-3790339, a Ritanserin (HY-10791) analog, is a potent and selective diacylglycerol kinase (DGKα) inhibitor with an IC50 of 9.6 μM. JNJ-3790339 has induction of toxicity in malignant cells, and improves ability to upregulate T cell activation[1].
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JNJ-3790339 | JNJ-3790339, a Ritanserin (HY-10791) analog, is a potent and selective diacylglycerol kinase (DGKα) inhibitor with an IC50 of 9.6 μM. JNJ-3790339 has induction of toxicity in malignant cells, and improves ability to upregulate T cell activation. | |||||||||||||||||||||
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References
Keywords
