94-52-0
Chemical Structure
5-Nitrobenzimidazole
- CAS No.: 94-52-0
- Formula:C7H5N3O2
- Molecular Weight:163.14
IUPAC Name: 6-nitro-1H-benzo[d]imidazole
InChIKey: XPAZGLFMMUODDK-UHFFFAOYSA-N
SMILES: O=[N+]([O-])C1=CC2=C(N=CN2)C=C1
Biological Activity: 5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine (HY-B0152) analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia[1][2].
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5-Nitrobenzimidazole | 99.74% | 5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine (HY-B0152) analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia. | ||||||||||||||||||||
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- [1]. Hsieh JF, et al. The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. Bioorg Med Chem. 2007 May 15;15(10):3450-6. [Content Brief]
- [2]. Deýlová D, et al. Voltammetric Determination of 4‐Nitrophenol and 5‐Nitrobenzimidazole Using Different Types of Silver Solid Amalgam Electrodes–A Comparative Study. Electroanalysis, 2011, 23(7): 1548-1555.
Keywords