97027-56-0
97027-56-0
Chemical Structure
NSC-80141
- CAS No.: 97027-56-0
- Formula:C13H9Cl2N
- Molecular Weight:250.12
IUPAC Name: 6,7-dichloro-9H-fluoren-2-amine
InChIKey: PAILPOTUYGAUEW-UHFFFAOYSA-N
SMILES: ClC=1C=C2C=3C=CC(N)=CC3CC2=CC1Cl
Biological Activity: NSC-80141 is a Kinesin-5 inhibitor. NSC-80141 exerts selective inhibitory activity against human kinesin-5 (HsEg5) (IC50: 9.4 μM), while shows weak inhibitory activity against Plasmodium kinesin-5 (PvEg5) (IC50: 27.3 μM). NSC-80141 serves as a tool compound for distinguishing human and Plasmodium homologous proteins[1].
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NSC-80141 | NSC-80141 is a Kinesin-5 inhibitor. NSC-80141 exerts selective inhibitory activity against human kinesin-5 (HsEg5) (IC50: 9.4 μM), while shows weak inhibitory activity against Plasmodium kinesin-5 (PvEg5) (IC50: 27.3 μM). NSC-80141 serves as a tool compound for distinguishing human and Plasmodium homologous proteins. | |||||||||||||||||||||
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