97205-34-0
Chemical Structure
Nebracetam
Synonym(s): WEB 1881 FU
- CAS No.: 97205-34-0
- Formula:C12H16N2O
- Molecular Weight:204.27
IUPAC Name: 4-(aminomethyl)-1-benzylpyrrolidin-2-one
InChIKey: LCAFGJGYCUMTGS-UHFFFAOYSA-N
SMILES: O=C1N(CC2=CC=CC=C2)CC(CN)C1
Biological Activity: Nebracetam (WEB 1881 FU) is an orally active M1 muscarinic receptor agonist. Nebracetam can induce an increase in intracellular Ca2+ concentration, with an EC50 value of 1.59 mM. Nebracetam exhibits neuroprotective activity and the ability to improve cognitive impairment. Nebracetam can be used in the research of neurological diseases such as Alzheimer's disease[1][2].
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Nebracetam | Nebracetam (WEB 1881 FU) is an orally active M1 muscarinic receptor agonist. Nebracetam can induce an increase in intracellular Ca2+ concentration, with an EC50 value of 1.59 mM. Nebracetam exhibits neuroprotective activity and the ability to improve cognitive impairment. Nebracetam can be used in the research of neurological diseases such as Alzheimer's disease. | |||||||||||||||||||||
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- [1]. Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55(1):177-80. [Content Brief]
- [2]. Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58(2):117-26. [Content Brief]
Keywords
