977-96-8
977-96-8
Chemical Structure
Pseudoisocyanine iodide
Synonym(s): 1,1'-Diethyl-2,2'-cyanine iodide; Decynium 22; Diethylcyanine iodide; Eastman 7851
- CAS No.: 977-96-8
- Formula:C23H23IN2
- Molecular Weight:454.35
IUPAC Name: (E)-1-ethyl-2-((1-ethylquinolin-2(1H)-ylidene)methyl)quinolin-1-ium iodide
InChIKey: GMYRVMSXMHEDTL-UHFFFAOYSA-M
SMILES: CCN1C2=CC=CC=C2C=C/C1=C\C3=[N+](C4=CC=CC=C4C=C3)CC.[I-]
Biological Activity: Pseudoisocyanine iodide (1,1'-Diethyl-2,2'-cyanine iodide) is an inhibitor of organic cation transporters (OCT1, OCT2, OCT3) and plasma membrane monoamine transporter (PMAT). Pseudoisocyanine iodide has antidepressant activity[1][2].
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Pseudoisocyanine iodide | 99.97% | Pseudoisocyanine iodide (1,1'-Diethyl-2,2'-cyanine iodide) is an inhibitor of organic cation transporters (OCT1, OCT2, OCT3) and plasma membrane monoamine transporter (PMAT). Pseudoisocyanine iodide has antidepressant activity. | ||||||||||||||||||||
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Pseudoisocyanine iodide (Standard) | ≥98% | Pseudoisocyanine iodide (Standard) is the analytical standard of Pseudoisocyanine (iodide) (HY-107740). This product is intended for research and analytical applications. Pseudoisocyanine iodide (1,1'-Diethyl-2,2'-cyanine iodide) is an inhibitor of organic cation transporters (OCT1, OCT2, OCT3) and plasma membrane monoamine transporter (PMAT). Pseudoisocyanine iodide has antidepressant activity. | ||||||||||||||||||||
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References
- [1]. Fraser-Spears R, et al. Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter. Eur J Pharmacol. 2019 Jan 5;842:351-364. [Content Brief]
- [2]. Horton RE, et al. Decynium-22 enhances SSRI-induced antidepressant-like effects in mice: uncovering novel targets to treat depression. J Neurosci. 2013 Jun 19;33(25):10534-43. [Content Brief]
