987-78-0
Chemical Structure
Citicoline
Synonym(s): Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine
- CAS No.: 987-78-0
- Formula:C14H26N4O11P2
- Molecular Weight:488.32
IUPAC Name: 2-(((((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)((hydroxyoxidophosphoryl)oxy)phosphoryl)oxy)-N,N,N-trimethylethan-1-aminium
InChIKey: RZZPDXZPRHQOCG-OJAKKHQRSA-N
SMILES: NC(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OCC[N+](C)(C)C)([O-])=O)(O)=O)O2)=NC1=O
Biological Activity: Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Citicoline | 99.88% | Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study. | ||||||||||||||||||||
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Citicoline (Standard) | 99.19% | Citicoline (Cytidine diphosphate-choline) (Standard) is the analytical standard of Citicoline. This product is intended for research and analytical applications. Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study. | ||||||||||||||||||||
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Citicoline-d9 | Citicoline-d9 (Cytidine diphosphate-choline-d9) is the deuterated-labeled Citicoline (HY-B0739). Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study. | |||||||||||||||||||||
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Similarity Score 0.89
HY-B0739ARCiticoline sodium (Standard) -
Similarity Score 0.82
HY-145780Cytidine 5′-diphosphoethanolamine -
Similarity Score 0.79
HY-113400Cytidine 5'-diphosphate -
Similarity Score 0.78
HY-N14428Fosfocytocin -
Similarity Score 0.76
HY-180634CMP-2-Aminoethylphosphonate -
Similarity Score 0.76
HY-115740Cytarabine triphosphate -
Similarity Score 0.76
HY-125818Cytidine-5'-triphosphate -
Similarity Score 0.76
HY-W754064Cytidine-5'-triphosphate-13C5 -
Similarity Score 0.75
HY-W008940RCytidine 5'-diphosphate disodium salt (Standard) -
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References
- [1]. Davinelli S, et al. Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells. Oxid Med Cell Longev. 2017;2017:2825703. [Content Brief]
- [2]. Karpova MN, et al. Increase of the seizure threshold in C57BL/6 mice after citicoline administration. Bull Exp Biol Med. 2015 Jan;158(3):315-7. [Content Brief]
- [3]. Zhong Z, et al. Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage. Front Cell Dev Biol. 2020 Aug 31;8:712. [Content Brief]
