99-83-2
Chemical Structure
α-Phellandrene
Synonym(s): alpha-Phellandrene
- CAS No.: 99-83-2
- Formula:C10H16
- Molecular Weight:136.23
IUPAC Name: 5-isopropyl-2-methylcyclohexa-1,3-diene
InChIKey: OGLDWXZKYODSOB-UHFFFAOYSA-N
SMILES: CC1=CCC(C=C1)C(C)C
Biological Activity: α-Phellandrene (alpha-Phellandrene) is an orally active monoterpenoid and insecticide. α-Phellandrene can be isolated from plant essential oils. α-Phellandrene induces Apoptosis and Autophagy. α-Phellandrene promotes cAMP signaling pathway and increases NO production. α-Phellandrene has anti-inflammatory and anticancer (sarcoma) activities. α-Phellandrene shows insecticidal activity against Lucilia cuprina L3. α-Phellandrene reduces mechanical hyperalgesia[1][2][3][4][5][6][7][8][9][10][11].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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α-Phellandrene | 85.70% | α-Phellandrene (alpha-Phellandrene) is an orally active monoterpenoid and insecticide. α-Phellandrene can be isolated from plant essential oils. α-Phellandrene induces Apoptosis and Autophagy. α-Phellandrene promotes cAMP signaling pathway and increases NO production. α-Phellandrene has anti-inflammatory and anticancer (sarcoma) activities. α-Phellandrene shows insecticidal activity against Lucilia cuprina L3. α-Phellandrene reduces mechanical hyperalgesia. | ||||||||||||||||||||
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Germacrene D | 93.34% | Germacrene D is isolated from Solidago canadensis. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles. | ||||||||||||||||||||
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(Rac)-Germacrene D | (Rac)-Germacrene D is a natural product that can be isolated from the genus Bursera. | |||||||||||||||||||||
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(-)-α-Cadinene | (-)-α-Cadinene is a sesquiterpene hydrocarbon that can be isolated from Japanese hops. (-)-α-Cadinene is a natural product. | |||||||||||||||||||||
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Phellandral | Phellandral is an aldehyde compound that can be found in Eucalyptus camaldulensis and Thymus seravschanicus. The phellandral-containing eucalyptus essential oil exhibits significant inhibitory effects on various plant pathogenic fungi, especially on Aspergillus flavus. Phellandral, together with other oxygenated monoterpenoids, constitutes an important basis for the antibacterial activity of the essential oil. | |||||||||||||||||||||
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β-Phellandrene | 99.43% | β-phellandrene is an orally active monocyclic monoterpenes. β-Phellandrene is obtained from Carum petroselinum. β-phellandrene has strong ability to kill pest. β-phellandrene can be used as oil additives, natural pesticides and synthetic materials. | ||||||||||||||||||||
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β-Phellandrene-d2 | β-Phellandrene-d2 is deuterated labeled β-Phellandrene (HY-N8573). β-phellandrene is an orally active monocyclic monoterpenes. β-Phellandrene is obtained from Carum petroselinum. β-phellandrene has strong ability to kill pest. β-phellandrene can be used as oil additives, natural pesticides and synthetic materials. | |||||||||||||||||||||
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(R)-(-)-α-Phellandrene | 85.8% | (R)-(-)-α-Phellandrene ((-)-α-Phellandrene) is an the (R)-(-)-stereoisomer of α-phellandrene. α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage. | ||||||||||||||||||||
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α-Terpinene (Standard) | 96.86% | α-Terpinene (Standard) is the analytical standard of α-Terpinene. This product is intended for research and analytical applications. α-Terpinene (Terpilene) is a monoterpene found in the essential oils of a large variety of foods and aromatic plants such as Mentha piperita. α-Terpinene is active against Trypanosoma evansi and has the potential for trypanosomosis treatment. α-Terpinene has antioxidant and antifungal properties. | ||||||||||||||||||||
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γ-Terpinene (Standard) | 96.63% | γ-Terpinene (Standard) is the analytical standard of γ-Terpinene. This product is intended for research and analytical applications. γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi. | ||||||||||||||||||||
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α-Thujene | 95.0% | α-Thujene is a hydrogenated monoterpene hydrocarbon. α-Thujene exists in the essential oils of fresh leaves of Crassocephalum rubens and leaves of Photinia serrulata. The essential oil from fresh Crassocephalum rubens leaves containing α-Thujene exhibits potent antibacterial activity. α-Thujene is used in studies on infections caused by Escherichia coli and Staphylococcus aureus. | ||||||||||||||||||||
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References
- [1]. Abdouli I, et al. TiO2 Catalyzed Dihydroxyacetone (DHA) Conversion in Water: Evidence That This Model Reaction Probes Basicity in Addition to Acidity. Molecules. 2022 Nov 24;27(23):8172. [Content Brief]
- [2]. Susanto AC, et al. α‑Phellandrene enhances the apoptosis of HT‑29 cells induced by 5‑fluorouracil by modulating the mitochondria‑dependent pathway. Oncol Rep. 2024 Apr;51(4):61. [Content Brief]
- [3]. Hsieh SL, et al. Induction of necrosis in human liver tumor cells by α-phellandrene. Nutr Cancer. 2014;66(6):970-9. [Content Brief]
- [4]. Lin JJ, et al. α-Phellandrene alters expression of genes associated with DNA damage, cell cycle, and apoptosis in murine leukemia WEHI-3 cells. Anticancer Res. 2014 Aug;34(8):4161-80. [Content Brief]
- [5]. Kang W, et al. Activation of cAMP Signaling in Response to α-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells. Int J Mol Sci. 2022 Aug 11;23(16):8959. [Content Brief]
- [6]. Hsieh LC, et al. Induction of α-phellandrene on autophagy in human liver tumor cells. Am J Chin Med. 2015;43(1):121-36. [Content Brief]
- [7]. Chaaban A, et al. Insecticide activity of Curcuma longa (leaves) essential oil and its major compound α-phellandrene against Lucilia cuprina larvae (Diptera: Calliphoridae): Histological and ultrastructural biomarkers assessment. Pestic Biochem Physiol. 2019 Jan;153:17-27. [Content Brief]
- [8]. Lin JJ, et al. Alpha-phellandrene promotes immune responses in normal mice through enhancing macrophage phagocytosis and natural killer cell activities. In Vivo. 2013 Nov-Dec;27(6):809-14. [Content Brief]
- [9]. Pinheiro-Neto FR, et al. α-Phellandrene exhibits antinociceptive and tumor-reducing effects in a mouse model of oncologic pain. Toxicol Appl Pharmacol. 2021 May 1;418:115497. [Content Brief]
- [10]. Gonçalves R L G, et al. α-Phellandrene attenuates tissular damage, oxidative stress, and TNF-α levels on acute model ifosfamide-induced hemorrhagic cystitis in mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, 393: 1835-1848.
- [11]. Siqueira HDS, et al. α-Phellandrene, a cyclic monoterpene, attenuates inflammatory response through neutrophil migration inhibition and mast cell degranulation. Life Sci. 2016 Sep 1;160:27-33. [Content Brief]