CAY10621
Based on 1 Customer Validation
CAY10621 (SKI 5C; compound 5c) is a specific sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 3.3 μM. CAY10621 is low toxic toward cells. CAY10621 has the potential for resistant cancer tumors research.
For research use only. We do not sell to patients.
- Purity : 99.3%
- CAS No.: 120005-55-2
- Formula: C26H45NO4
- Molecular Weight:435.64
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Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
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SphK1 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
3.3 μM
Compound: 5c
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Inhibition of EGFP-fused human SPHK1 expressed in CHO cells
Inhibition of EGFP-fused human SPHK1 expressed in CHO cells
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[PMID: 19469544] |
Chemical Information
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CAS No. 120005-55-2
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Appearance Liquid
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Molecular Weight 435.64
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Formula C26H45NO4
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Color Colorless to light yellow
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SMILES
O=C(N1C(C)(C)OC[C@H]1C(C#CCCCCCCCCCCCCC)=O)OC(C)(C)C
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Synonyms
SKI 5C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (263 KB)
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SDS (545 KB)
- English - EN (545 KB)
- Français - FR (545 KB)
- Deutsch - DE (545 KB)
- Norwegian - NO (545 KB)
- Español - ES (545 KB)
- Swedish - SV (545 KB)
- Italian - IT (545 KB)
- Korean - KR (545 KB)
- Portuguese - PT (545 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CAY10621 Related Classifications
HY-117563 Related Classifications
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