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Cat. No.: HY-P3730

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Cdk2/Cyclin Inhibitory Peptide I

Cdk2/Cyclin Inhibitory Peptide I (Tat-LFG), a CDK2 inhibitor, kills U2OS osteosarcoma cells in a dose-dependent manner.

For research use only. We do not sell to patients.

CAS No.: 237392-84-6
Formula: C₁₁₁H₁₉₆N₄₈O₂₃
Molecular Weight:2571.05

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cdk2/Cyclin Inhibitory Peptide I Chemical Structure

CAS No.: 237392-84-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cdk2/Cyclin Inhibitory Peptide I (Tat-LFG), a CDK2 inhibitor, kills U2OS osteosarcoma cells in a dose-dependent manner^[1].

IC₅₀ & Target

CDK2^[1].

All CDK Isoforms :

In Vitro

Cdk2/Cyclin Inhibitory Peptide I (0-150 μM; 24 h) kills U2OS osteosarcoma cells in a dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

U2OS osteosarcoma cells
Concentration:

0-150 µM
Incubation Time:

24 h
Result:

Exhibited good activity to kill U2OS osteosarcoma cells.

Chemical Information

CAS No. 237392-84-6
Molecular Weight 2571.05
Formula C₁₁₁H₁₉₆N₄₈O₂₃
Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Pro-Val-Lys-Arg-Arg-Leu-Phe-Gly
Sequence Shortening

YGRKKRRQRRRGPVKRRLFG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen YN, et al. Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4325-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Cdk2/Cyclin Inhibitory Peptide I

All CDK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Cdk2/Cyclin Inhibitory Peptide I Related Classifications

HY-P3730 Related Classifications