ATM/ATR Ligand
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ATR ligand 2
0 ImagesArt. -Nr.: HY-182017CAS. Nr.: 3060178-60-8
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ZH25
0 ImagesArt. -Nr.: HY-184294CAS. Nr.: 3037598-39-0ZH25 is an ATR kinase inhibitor with antiproliferative activity against ATM-deficient cancer cells. ZH25 induces DNA damage, reduces G2/M phase cell proportion, upregulates γH2AX, Cleaved-Caspase3, and Cleaved-PARP. ZH25 functions as an ATR kinase binding ligand for ATR-PROTAC degrader design. ZH25 can be used for the research of atm-deficient cancer.
