Ac-H-FluNox
Based on 1 Customer Validation
Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins.
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- Reinheit: 99.88%
- CAS. Nr.: 2897614-60-5
- Formel: C27H21F2NO6
- Molecular Weight:493.46
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Speicherung:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Ac-H-FluNox (10 μM; 30 min) detects dose-dependent, NO-induced labile heme release in HeLa cells[1].
Ac-H-FluNox (10 μM; 30 min) detects labile heme accumulation in FLVCR1a-knockdown SH-SY5Y cells treated with ALA+FAC[1].
Ac-H-FluNox (10 μM; 30 min) detects elevated labile heme levels in erastin-induced ferroptotic HT1080 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2897614-60-5
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Appearance Solid
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Molecular Weight 493.46
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Formel C27H21F2NO6
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Color White to off-white
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SMILES
O=C1OC2(C3=C1C=CC=C3)C4=CC=C(C=C4OC5=CC([N+]6(CCC(F)(CC6)F)[O-])=CC=C52)OC(C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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