AE-ITU dihydrobromide
Based on 1 Customer Validation
AE-ITU dihydrobromide is the dihydrobromide form of AE-ITU. AE-ITU dihydrobromide is a selective inhibitor for inducible NO synthase (iNOS), and attenuates the liver dysfunction caused by endotoxaemia in rats.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.0%
- CAS. Nr.: 56-10-0
- Formel: C3H11Br2N3S
- Molecular Weight:281.01
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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S-EIT hydrobromideBiochemical Reagent -
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L-NILNO Synthase Inhibitor -
HY-107584
BYK 191023 dihydrochlorideInducible Nitric-Oxide Synthase (iNOS) Inhibitor -
HY-101304
S-Isopropylisothiourea hydrobromideNOS Inhibitor -
HY-138564
NOS-IN-1NO Synthase Inhibitor -
HY-138454
MEG hemisulfateiNOS Inhibitor -
HY-100986
L-NIO dihydrochlorideNOS Inhibitor
Biologische Aktivität
Beschreibung
IC50 & Target
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iNOS |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:LPS (HY-D1056)-administrated Wistar rats[1]
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Dosage:1 mg/kg
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Administration:i.v., 1 mg/kg/h for 1 hour
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Result:Reduced the serum levels of bilirubin, serum nitrite, GOT, GPT and γGT caused by LPS, inhibited iNOS in lung and liver homogenates.
Chemical Information
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CAS. Nr. 56-10-0
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Appearance Solid
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Molecular Weight 281.01
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Formel C3H11Br2N3S
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Color White to yellow
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SMILES
NC(SCCN)=N.[H]Br.[H]Br
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
In Vitro:
H2O : ≥ 100 mg/mL (355.86 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 3.5586 mL | 17.7930 mL | 35.5859 mL | 88.9648 mL |
| 5 mM | 0.7117 mL | 3.5586 mL | 7.1172 mL | 17.7930 mL | |
| 10 mM | 0.3559 mL | 1.7793 mL | 3.5586 mL | 8.8965 mL | |
| 15 mM | 0.2372 mL | 1.1862 mL | 2.3724 mL | 5.9310 mL | |
| 20 mM | 0.1779 mL | 0.8896 mL | 1.7793 mL | 4.4482 mL | |
| 25 mM | 0.1423 mL | 0.7117 mL | 1.4234 mL | 3.5586 mL | |
| 30 mM | 0.1186 mL | 0.5931 mL | 1.1862 mL | 2.9655 mL | |
| 40 mM | 0.0890 mL | 0.4448 mL | 0.8896 mL | 2.2241 mL | |
| 50 mM | 0.0712 mL | 0.3559 mL | 0.7117 mL | 1.7793 mL | |
| 60 mM | 0.0593 mL | 0.2965 mL | 0.5931 mL | 1.4827 mL | |
| 80 mM | 0.0445 mL | 0.2224 mL | 0.4448 mL | 1.1121 mL | |
| 100 mM | 0.0356 mL | 0.1779 mL | 0.3559 mL | 0.8896 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
AE-ITU dihydrobromide Related Classifications
HY-131929 Related Classifications
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