AR antagonist 7
AR antagonist 7 (86) is an androgen receptor (AR) antagonist that can be used in the research of hair loss.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 876759-97-6
- Formel: C16H12F3NO2
- Molecular Weight:307.27
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
299 nM
Compound: 6l
|
Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced response
Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced response
|
[PMID: 19286380] |
| Sf9 | IC50 |
69 nM
Compound: 6l
|
Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell system
Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell system
|
[PMID: 19286380] |
Chemical Information
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CAS. Nr. 876759-97-6
-
Molecular Weight 307.27
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Formel C16H12F3NO2
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SMILES
N#CC1=CC=C(OC2=CC=C(C)C=C2OC)C=C1C(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)