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Art. -Nr.: HY-121047

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Azaleucine

Azaleucine is an inhibitor of leucyl-tRNA synthetase. Azaleucine acts as an alternative substrate for this enzyme, undergoes pyrophosphate exchange reaction, and competes with leucine for the active site of the enzyme.

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CAS. Nr.: 4746-36-5
Formel: C₅H₁₂N₂O₂
Molecular Weight:132.16

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Azaleucine Chemical Structure

CAS. Nr.: 4746-36-5

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

DL-azaleucine (10 mM) serves as an alternative substrate for leucyl-tRNA synthetase from Aesculus hippocastanum cotyledons, supporting 20% of the pyrophosphate exchange activity seen with leucine at a concentration of 10 mM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 4746-36-5
Molecular Weight 132.16
Formel C₅H₁₂N₂O₂
SMILES

O=C(O)C(N)CN(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Anderson JW, et al. Properties and substrate specificity of the leucyl-, the threonyl- and the valyl-transfer-ribonucleic acid synthetases from Aesculus species. The Biochemical journal. 1970 Oct;119(4):691-7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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