CoelPhos
CoelPhos is the cell-impermeable coelenterazine derivative. CoelPhos specifically recognizes extracellular GLuc and generates luminescent signals. CoelPhos is a practical bioluminescent tool for monitoring exocytic processes such as cell surface membrane fusion.
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- CAS. Nr.: 1643661-02-2
- Formel: C33H33N6O7P
- Molecular Weight:656.62
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
CoelPhos generates a detectable bioluminescent signal in HeLa cells expressing outer membrane-localized GLucM23, with an activity approximately 3-4% of that of native coelenterazine[1].
CoelPhos cannot cross the cell membrane, as it fails to generate a bioluminescent signal in HeLa cells expressing endoplasmic reticulum-localized GLucER[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1643661-02-2
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Molecular Weight 656.62
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Formel C33H33N6O7P
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SMILES
O=C1C(CC2=CC=C(C=C2)OCCCN3N=NC(COCP(O)(O)=O)=C3)=NC4=C(CC5=CC=CC=C5)NC(C6=CC=C(O)C=C6)=CN14
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)