Deacetylforskolin
Deacetylforskolin is a deacetylated derivative of forskolin (HY-15371) that can be extracted from C. forskohlii. Deacetylforskolin activates rat adipocyte adenylyl cyclase (IC50 = 20 µM), inhibits glucose transport in rat adipocyte plasma membranes and exhibits antihypertensive activity.
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- CAS. Nr.: 64657-20-1
- Formel: C20H32O6
- Molecular Weight:368.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 64657-20-1
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Molecular Weight 368.46
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Formel C20H32O6
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SMILES
O[C@@]([C@@]([C@H]1O)(O[C@@]2(C)C=C)C)(C(C2)=O)[C@]([C@@](C3(C)C)([H])[C@@H]1O)([C@H](CC3)O)C
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Synonyms
7-Deacetylforskolin
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Joost HG, et al. Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action. Mol Pharmacol. 1988 Apr;33(4):449-53. [Content Brief]
[2]. Bhat SV, et al. The antihypertensive and positive inotropic diterpene forskolin: effects of structural modifications on its activity. J Med Chem. 1983 Apr;26(4):486-92. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Deacetylforskolin Related Classifications
HY-137934 Related Classifications
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