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Art. -Nr.: HY-184950

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eEF2K ligand-1

eEF2K ligand-1 is a PROTAC target protein ligand that targets eEF2K, and it is applicable to research related to PROTAC synthesis. eEF2K ligand-1 serves as the target protein of PROTAC eEF2K degrader-1 (HY-146324).

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CAS. Nr.: 2458170-55-1
Formel: C₁₀H₁₁N₅O₃
Molecular Weight:249.23

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

eEF2K ligand-1 Chemical Structure

CAS. Nr.: 2458170-55-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

CaMK III/eEF-2K

Alle CaMK Isoform-spezifische Produkte anzeigen :

In Vitro

eEF2K ligand-1 serves as the target protein for PROTAC eEF2K degrader-1 (HY-146324). PROTAC eEF2K Degrader-1 (Compound 11l) is a PROTAC small molecule targeting eEF2K, which mediates eEF2K degradation and induces apoptosis in MDA-MB-231 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2458170-55-1
Molecular Weight 249.23
Formel C₁₀H₁₁N₅O₃
SMILES

O=C(C1=C(N)N=C(C(C(N2)=O)=C1)N(CC)C2=O)N
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Liu Y, et al. Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells. European Journal of Medicinal Chemistry. 2020;204:112505.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
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eEF2K ligand-1

Alle CaMK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

eEF2K ligand-1 Related Classifications

HY-184950 Related Classifications