Erlosiban
Erlosiban (OBE001) is an orally active non-peptide type oxytocin receptor antagonist. Erlosiban inhibits the increase of intracellular calcium concentration, thereby reducing uterine smooth muscle contraction. Erlosiban can be used for research on premature birth and to improve embryo implantation and pregnancy rate in assisted reproductive technology (AR).
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- CAS. Nr.: 1477482-19-1
- Formel: C20H22N2O3
- Molecular Weight:338.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 1477482-19-1
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Molecular Weight 338.40
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Formel C20H22N2O3
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SMILES
O=C(N1C/C(C[C@H]1CO)=N\OC)C2=CC=C(C3=CC=CC=C3C)C=C2
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Synonyms
OBE001
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Pohl O, et al. Effects of the Oral Oxytocin Receptor Antagonist Tocolytic OBE001 on Reproduction in Rats. Reprod Sci. 2016 Apr;23(4):439-47. [Content Brief]
[2]. Pohl O, et al. Pharmacokinetic interactions of OBE001 and betamethasone in healthy female volunteers. J Clin Pharm Ther. 2015 Jun;40(3):328-32. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Erlosiban Related Classifications
HY-16741 Related Classifications
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