ES-8891

ES-8891 is a renin inhibitor. Oral administration of ES-8891 to normotensive sodium-depleted macaques for one week significantly reduced plasma renin activity, immunoreactive renin concentrations, and plasma angiotensin I concentrations, while mean blood pressure decreased significantly, without significant changes in heart rate. ES-8891 regulates blood pressure by inhibiting plasma renin levels and renal renin synthesis.

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  • CAS. Nr.: 129445-88-1
  • Formel: C42H60N6O6S
  • Molecular Weight:777.03
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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