ECPAS - Ecm29 proteasome adaptor and scaffold Gene

Also Known as ECM29; KIAA0368

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23392

About ECPAS

Cytogenetic location: 9q31.3 Genomic coordinates (GRCh38): 9:111,360,685-111,484,383 (from NCBI)

This gene has 7 transcripts (splice variants), 210 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 17.3), fat (RPKM 15.6) and 25 other tissues.

Summary

Enables Proteasome binding activity. Involved in ubiquitin-dependent ERAD pathway. Located in several cellular components, including centrosome; cytoplasmic vesicle; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ECPAS Products (4)

mRNA Protein Name
NM_001363756.2 NP_001350685.1 proteasome adapter and scaffold protein ECM29 isoform 2
NM_001364929.1 NP_001351858.1 proteasome adapter and scaffold protein ECM29 isoform 3
NM_001364930.1 NP_001351859.1 proteasome adapter and scaffold protein ECM29 isoform 3
NM_001364931.1 NP_001351860.1 proteasome adapter and scaffold protein ECM29 isoform 4

ECPAS Protein Structure

Ecm29

Ecm29: Proteasome stabiliser (10 - 516)

Vac14_Fab1_bd

Vac14_Fab1_bd: Vacuolar 14 Fab1-binding region (1146 - 1223)

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  • 1839 a.a.
Protein Preferred Names Protein Names

proteasome adapter and scaffold protein ECM29

  • ECM29 homolog, proteasome accessory protein

ECPAS Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
ECPAS Q5VYK3 TNFRSF10D Homo sapiens Q9UBN6
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 TNFRSF10D Homo sapiens Q9UBN6
Y2H Array
32296183
Intra
ECPAS Q5VYK3 TNFRSF10D Homo sapiens Q9UBN6
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 CMTM6 Homo sapiens Q9NX76
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 CMTM6 Homo sapiens Q9NX76
Y2H Array
32296183
Intra
ECPAS Q5VYK3 CMTM6 Homo sapiens Q9NX76
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 AGTRAP Homo sapiens Q6RW13-2
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 AGTRAP Homo sapiens Q6RW13-2
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 AGTRAP Homo sapiens Q6RW13-2
Y2H Array
32296183
Intra
ECPAS Q5VYK3 CMTM5 Homo sapiens Q96DZ9-2
Y2H Array
32296183
Intra
ECPAS Q5VYK3 CMTM5 Homo sapiens Q96DZ9-2
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 CMTM5 Homo sapiens Q96DZ9-2
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 DGAT2L6 Homo sapiens Q6ZPD8
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 DGAT2L6 Homo sapiens Q6ZPD8
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 DGAT2L6 Homo sapiens Q6ZPD8
Y2H Array
32296183
Intra
ECPAS Q5VYK3 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra
ECPAS Q5VYK3 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 HSD17B13 Homo sapiens Q7Z5P4
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 CMTM5 Homo sapiens Q96DZ9
Y2H Prey Pooling
25416956
Intra
ECPAS Q5VYK3 CMTM5 Homo sapiens Q96DZ9
Validated Y2H
25416956
Intra
ECPAS Q5VYK3 BSND Homo sapiens Q8WZ55
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 BSND Homo sapiens Q8WZ55
Y2H Array
32296183
Intra
ECPAS Q5VYK3 BSND Homo sapiens Q8WZ55
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 MAL2 Homo sapiens Q969L2
Y2H Prey Pooling
32296183
Intra
ECPAS Q5VYK3 MAL2 Homo sapiens Q969L2
Validated Y2H
32296183
Intra
ECPAS Q5VYK3 MAL2 Homo sapiens Q969L2
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04145 ECPAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ECPAS VGNC VGNC:30551
Canis familiaris ECPAS VGNC VGNC:42346
Mus musculus ECPAS MGD MGI:2140220
Macaca mulatta ECPAS VGNC VGNC:72137
Rattus norvegicus ECPAS RGD RGD:1306148
Felis catus ECPAS VGNC VGNC:61713
Others ECPAS NCBI