NEURL4 - neuralized E3 ubiquitin protein ligase 4 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84461

About NEURL4

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,315,628-7,329,335 (from NCBI)

This gene has 14 transcripts (splice variants), 1 gene allele, 182 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 8.3), testis (RPKM 8.0) and 25 other tissues.

Summary

The protein encoded by this gene is predicted and it includes two isoforms resulting from two alternatively spliced transcript variants. [provided by RefSeq, Jul 2008]

NEURL4 Products (2)

mRNA Protein Name
NM_001005408.2 NP_001005408.1 neuralized-like protein 4 isoform 2
NM_032442.3 NP_115818.2 neuralized-like protein 4 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
22441691 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NEURL4 Protein Structure

Neuralized

Neuralized: Neuralized (44 - 111)

Neuralized

Neuralized: Neuralized (318 - 387)

Neuralized

Neuralized: Neuralized (521 - 590)

Neuralized

Neuralized: Neuralized (717 - 786)

Neuralized

Neuralized: Neuralized (915 - 980)

Neuralized

Neuralized: Neuralized (1132 - 1198)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1562 a.a.
Protein Preferred Names Protein Names

neuralized-like protein 4

  • neuralized homolog 4

NEURL4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
NEURL4 Q96JN8 CCP110 Homo sapiens O43303
Pull Down
22441691
Intra
NEURL4 Q96JN8 CCP110 Homo sapiens O43303
Anti Bait CoIP
22441691
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Retinitis Pigmentosa 75

  • RP75

  • Retinitis Pigmentosa, Type 75
Angelman Syndrome

  • AS

  • Happy Puppet Syndrome

  • Happy Puppet Syndrome, Formerly

  • Puppetlike Syndrome
Dyschromatosis Universalis Hereditaria

  • Duh
Atrophic Rhinitis

  • Rhinitis, Atrophic

  • Ozena

  • Rhinitis Sicca

  • Dry Rhinitis

  • Ozaena
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS09223 NEURL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NEURL4 VGNC VGNC:54462
Macaca mulatta NEURL4 VGNC VGNC:82197
Mus musculus NEURL4 MGD MGI:1921092
Rattus norvegicus NEURL4 RGD RGD:1308056
Felis catus NEURL4 VGNC VGNC:99289
Others NEURL4 NCBI