PRRC2B - proline rich coiled-coil 2B Gene

Also Known as BAT2L; BAT2L1; LQFBS-1; KIAA0515

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84726

About PRRC2B

Cytogenetic location: 9q34.13 Genomic coordinates (GRCh38): 9:131,373,651-131,500,193 (from NCBI)

This gene has 10 transcripts (splice variants), 210 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 18.3), ovary (RPKM 17.4) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in cell differentiation. Predicted to act upstream of or within in utero embryonic development. [provided by Alliance of Genome Resources, Apr 2022]

PRRC2B Products (5)

mRNA Protein Name
NM_001384818.1 NP_001371747.1 protein PRRC2B isoform 1
NM_001384821.1 NP_001371750.1 protein PRRC2B isoform 2
NM_001384822.1 NP_001371751.1 protein PRRC2B isoform 3
NM_001384823.1 NP_001371752.1 protein PRRC2B isoform 4
NM_013318.4 NP_037450.2 protein PRRC2B isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRRC2B Protein Structure

BAT2_N

BAT2_N: BAT2 N-terminus (1 - 192)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2229 a.a.
Protein Preferred Names Protein Names

protein PRRC2B

  • HLA-B associated transcript 2-like

PRRC2B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
PRRC2B Q5JSZ5 ZER1 Homo sapiens Q7Z7L7
Anti Tag CoIP
33961781
Intra
PRRC2B Q5JSZ5 EHMT2 Homo sapiens Q96KQ7
Pull Down
16189514
Intra
PRRC2B Q5JSZ5 ATXN1 Homo sapiens P54253
Y2H
16713569
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 2

  • Aoa2

  • Ataxia With Oculomotor Apraxia Type 2

  • Scar1

  • SCAN2

  • Ataxia-Oculomotor Apraxia 2

  • Ataxia-Ocular Apraxia 2

  • Ataxia-Oculomotor Apraxia Type 2

  • Scan 2

  • Spinocerebellar Ataxia With Axonal Neuropathy Type 2

  • Spinocerebellar Ataxia, Autosomal Recessive 1, Formerly

  • Scar1, Formerly

  • Autosomal Recessive Spinocerebellar Ataxia-1

  • Spinocerebellar Ataxia, Autosomal Recessive, 1

  • Ataxia-Ocular Apraxia-2

  • Spinocerebellar Ataxia, Autosomal Recessive 1
Spinocerebellar Ataxia 36

  • Spinocerebellar Ataxia Type 36

  • SCA36

  • Asidan Ataxia

  • Costa De Morte Ataxia

  • Asidan

  • Ataxia, Spinocerebellar, Type 36
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS11237 PRRC2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PRRC2B MGD MGI:1923304
Canis familiaris PRRC2B VGNC VGNC:45053
Rattus norvegicus PRRC2B RGD RGD:1595906
Bos taurus PRRC2B VGNC VGNC:33405
Macaca mulatta PRRC2B VGNC VGNC:76327
Others PRRC2B NCBI